EEF1G Protein (AA 1-437) (His tag)

Catalog No. ABIN5853812

Product Details

Target: EEF1G (Eukaryotic Translation Elongation Factor 1 gamma (EEF1G))

Protein Type: Recombinant

Protein Characteristics: AA 1-437

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This EEF1G protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAAGTLY TYPENWRAFK ALIAAQYSGA QVRVLSAPPH FHFGQTNRTP EFLRKFPAGK VPAFEGDDGF CVFESNAIAY YVSNEELRGS TPEAAAQVVQ WVSFADSDIV PPASTWVFPT LGIMHHNKQA TENAKEEVRR ILGLLDAYLK TRTFLVGERV TLADITVVCT LLWLYKQVLE PSFRQAFPNT NRWFLTCINQ PQFRAVLGEV KLCEKMAQFD AKKFAETQPK KDTPRKEKGS REEKQKPQAE RKEEKKAAAP APEEEMDECE QALAAEPKAK DPFAHLPKST FVLDEFKRKY SNEDTLSVAL PYFWEHFDKD GWSLWYSEYR FPEELTQTFM SCNLITGMFQ RLDKLRKNAF ASVILFGTNN SSSISGVWVF RGQELAFPLS PDWQVDYESY TWRKLDPGSE ETQTLVREYF SWEGAFQHVG KAFNQGKIFK

Purity: > 90 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1  mM DTT

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: EEF1G (Eukaryotic Translation Elongation Factor 1 gamma (EEF1G))

Alternative Name: EEF1G (EEF1G Products)

Synonyms: EF1G Protein, GIG35 Protein, eEF-1 gamma Protein, db03h10 Protein, fk76a09 Protein, mg:db03h10 Protein, wu:fk76a09 Protein, 2610301D06Rik Protein, AA407312 Protein, eef1g Protein, ef1g Protein, gig35 Protein, eukaryotic translation elongation factor 1 gamma Protein, eukaryotic translation elongation factor 1 gamma L homeolog Protein, eukaryotic translation elongation factor 1 gamma S homeolog Protein, EEF1G Protein, eef1g Protein, Eef1g Protein, eef1g.L Protein, eef1g.S Protein, EHI_119540 Protein, CMU_014590 Protein

Background: Elongation factor 1-gamma, also known as EEF1G, is a multi-protein complex that is responsible for the delivery of aminoacyl-tRNAs to the ribosome. This subunit contains an N-terminal glutathione transferase domain, which may be involved in regulating the assembly of multisubunit complexes containing this elongation factor and aminoacyl-tRNA synthetases. Increased expression of EEF1G is associated with pancreatic cancer, suggesting a possible role for EEF1G in the oncogenic transformation process. Recombinant human EEF1G protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 52.5 kDa (460aa)

NCBI Accession: NP_001395

UniProt: P26641