HCV Core Protein Protein (AA 1-120) (His tag)
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- Target See all HCV Core Protein (HCV C) Proteins
- HCV Core Protein (HCV C) (Hepatitis C Virus Core Protein (HCV C))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-120
- Origin
- Hepatitis C Virus (HCV)
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HCV Core Protein protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MSTNPKPQRK TKRNTNRRPQ DVKFPGGGQI VGGVYLLPRR GPRLGVRATR KTSERSQPRG RRQPIPKARR PEGRTWAQPG YPWPLYGNEG CGWAGWLLSP RGSRPSWGPT DPRRRSRNLG
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product HCV C Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- HCV Core Protein (HCV C) (Hepatitis C Virus Core Protein (HCV C))
- Alternative Name
- HCV-Core (HCV C Products)
- Target Type
- Viral Protein
- Background
- HCV-Core protein packages viral RNA to form a viral nucleocapsid, and promotes virion budding. It modulates viral translation initiation by interacting with HCV IRES and 40S ribosomal subunit and also regulates many host cellular functions such as signaling pathways and apoptosis. HCV-Core prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation. Recombinant Hepatitis C virus Core protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 15.7 kDa (140aa)
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