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HMGN3 Protein (AA 1-77) (His tag)

HMGN3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN5853856
  • Target See all HMGN3 Proteins
    HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-77
    Origin
    • 5
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This HMGN3 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MGSMPKRKSP ENTEGKDGSK VTKQEPTRRS ARLSAKPAPP KPEPKPRKTS AKKEPGAKIS RGAKGKKEEK QEAGKEGTEN
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product HMGN3 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Liquid. 20  mM Tris-HCl buffer (  pH 7.0) containing 10 % glycerol
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))
    Alternative Name
    HMGN3 (HMGN3 Products)
    Synonyms
    Trip7 Protein, PNAS-25 Protein, TRIP7 Protein, 1110002A15Rik Protein, 6330514M13Rik Protein, BB071015 Protein, high mobility group nucleosomal binding domain 3 L homeolog Protein, high mobility group nucleosomal binding domain 3 Protein, hmgn3.L Protein, HMGN3 Protein, Hmgn3 Protein
    Background
    HMGN3, also known as high mobility group nucleosomal binding domain 3, binds thyroid hormone receptor beta, but only in the presence of thyroid hormone. Thyroid hormone receptors are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. It is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Recombinant human HMGN3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
    Molecular Weight
    10.8 kDa(100aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_620058
    UniProt
    Q15651
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