TIAL1 Protein (AA 1-375) (His tag)

Catalog No. ABIN5854001

Product Details

Target: TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))

Protein Type: Recombinant

Protein Characteristics: AA 1-375

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This TIAL1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMMEDDGQ PRTLYVGNLS RDVTEVLILQ LFSQIGPCKS CKMITEHTSN DPYCFVEFYE HRDAAAALAA MNGRKILGKE VKVNWATTPS SQKKDTSNHF HVFVGDLSPE ITTEDIKSAF APFGKISDAR VVKDMATGKS KGYGFVSFYN KLDAENAIVH MGGQWLGGRQ IRTNWATRKP PAPKSTQENN TKQLRFEDVV NQSSPKNCTV YCGGIASGLT DQLMRQTFSP FGQIMEIRVF PEKGYSFVRF STHESAAHAI VSVNGTTIEG HVVKCYWGKE SPDMTKNFQQ VDYSQWGQWS QVYGNPQQYG QYMANGWQVP PYGVYGQPWN QQGFGVDQSP SAAWMGGFGA QPPQGQAPPP VIPPPNQAGY GMASYQTQ

Purity: > 90 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate buffered saline (  pH 7.4) containing, 50 % glycerol, 2  mM DTT, 1  mM EDTA

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))

Alternative Name: TIAL1 (TIAL1 Products)

Synonyms: TCBP Protein, TIAR Protein, 5330433G13Rik Protein, AL033329 Protein, mTIAR Protein, zgc:66130 Protein, tcbp Protein, tiar Protein, TIA1 cytotoxic granule associated RNA binding protein like 1 Protein, Tia1 cytotoxic granule-associated RNA binding protein-like 1 Protein, TIA1 cytotoxic granule-associated RNA binding protein-like 1 Protein, TIAL1 Protein, Tial1 Protein, tial1 Protein

Background: TIAL1 is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing. Recombinant human TIAL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 44.0kDa (398aa) confirmed by MALDI-TOF

NCBI Accession: NP_003243

UniProt: Q01085