NAPSA Protein (AA 64-420) (His tag)

Catalog No. ABIN5854014

Product Details

Target: NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Protein Type: Recombinant

Protein Characteristics: AA 64-420

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This NAPSA protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSKPIFVPL SNYRDVQYFG EIGLGTPPQN FTVAFDTGSS NLWVPSRRCH FFSVPCWLHH RFDPKASSSF QANGTKFAIQ YGTGRVDGIL SEDKLTIGGI KGASVIFGEA LWEPSLVFAF AHFDGILGLG FPILSVEGVR PPMDVLVEQG LLDKPVFSFY LNRDPEEPDG GELVLGGSDP AHYIPPLTFV PVTVPAYWQI HMERVKVGPG LTLCAKGCAA ILDTGTSLIT GPTEEIRALH AAIGGIPLLA GEYIILCSEI PKLPAVSFLL GGVWFNLTAH DYVIQTTRNG VRLCLSGFQA LDVPPPAGPF WILGDVFLGT YVAVFDRGDM KSSARVGLAR ARTRGADLGW GETAQAQFPG

Purity: > 90 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Denatured

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl (  pH 8.0) containing 10 % glycerol

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Alternative Name: NAPSA (NAPSA Products)

Synonyms: KAP Protein, Kdap Protein, NAP1 Protein, NAPA Protein, SNAPA Protein, pronapsin Protein, kap Protein, kdap Protein, nap1 Protein, napa Protein, napsa Protein, snapa Protein, napsin A aspartic peptidase Protein, napsin A aspartic peptidase L homeolog Protein, NAPSA Protein, Napsa Protein, napsa.L Protein

Background: NAPSA belongs to the peptidase A1 family and may be involved in processing of pneumocyte surfactant precursors. The activation peptides of aspartic proteinases plays role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional, glycosylated aspartic proteinase precursor containing an RGD motif and an additional 18 residues at its C-terminus. Recombinant human NAPSA protein, fused to His-tag at N-terminus, was expressed in E.coli.

Molecular Weight: 40.9kDa (380aa)

NCBI Accession: NP_004842

UniProt: O96009

Pathways: Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis