UBLCP1 Protein (AA 1-318) (His tag)

Catalog No. ABIN5854204

Product Details

Target: UBLCP1 (Ubiquitin-Like Domain Containing CTD Phosphatase 1 (UBLCP1))

Protein Type: Recombinant

Protein Characteristics: AA 1-318

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This UBLCP1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMALPIIV KWGGQEYSVT TLSEDDTVLD LKQFLKTLTG VLPERQKLLG LKVKGKPAEN DVKLGALKLK PNTKIMMMGT REESLEDVLG PPPDNDDVVN DFDIEDEVVE VENREENLLK ISRRVKEYKV EILNPPREGK KLLVLDVDYT LFDHRSCAET GVELMRPYLH EFLTSAYEDY DIVIWSATNM KWIEAKMKEL GVSTNANYKI TFMLDSAAMI TVHTPRRGLI DVKPLGVIWG KFSEFYSKKN TIMFDDIGRN FLMNPQNGLK IRPFMKAHLN RDKDKELLKL TQYLKEIAKL DDFLDLNHKY WERYLSKKQG Q

Purity: > 85 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid, In Phosphate buffered saline (  pH 7.4) containing 10 % glycerol, 1  mM DTT

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: UBLCP1 (Ubiquitin-Like Domain Containing CTD Phosphatase 1 (UBLCP1))

Alternative Name: UBLCP1 (UBLCP1 Products)

Synonyms: UBLCP1 Protein, DKFZp459P2311 Protein, wu:fb33g09 Protein, zgc:86634 Protein, CPUB1 Protein, 4930527B16Rik Protein, 8430435I17Rik Protein, BC002236 Protein, RGD1310386 Protein, ubiquitin like domain containing CTD phosphatase 1 Protein, ubiquitin-like domain containing CTD phosphatase 1 Protein, ubiquitin like domain containing CTD phosphatase 1 S homeolog Protein, ublcp1 Protein, Ublcp1 Protein, UBLCP1 Protein, ublcp1.S Protein

Background: UBLCP1 also known as ubiquitin-like domain-containing CTD phosphatase 1. This protein dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome. Recombinant human UBLCP1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 39.2kDa (341aa) confirmed by MALDI-TOF

NCBI Accession: NP_659486

UniProt: Q8WVY7