SLUG Protein (AA 1-268) (His tag)

Catalog No. ABIN5854222

Product Details

Target: SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))

Protein Type: Recombinant

Protein Characteristics: AA 1-268

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This SLUG protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMPRSFLV KKHFNASKKP NYSELDTHTV IISPYLYESY SMPVIPQPEI LSSGAYSPIT VWTTAAPFHA QLPNGLSPLS GYSSSLGRVS PPPPSDTSSK DHSGSESPIS DEEERLQSKL SDPHAIEAEK FQCNLCNKTY STFSGLAKHK QLHCDAQSRK SFSCKYCDKE YVSLGALKMH IRTHTLPCVC KICGKAFSRP WLLQGHIRTH TGEKPFSCPH CNRAFADRSN LRAHLQTHSD VKKYQCKNCS KTFSRMSLLH KHEESGCCVA H

Purity: > 80 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid, In 20  mM Tris-HCl Buffer (  pH 8.0) containing 10 % glycerol

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))

Alternative Name: SNAI2 (SNAI2 Products)

Synonyms: Slug Protein, Slugh Protein, Snail2 Protein, snail family transcriptional repressor 2 Protein, snail family zinc finger 2 Protein, Snai2 Protein

Background: SNAI2 also known as Zinc finger protein SNAI2. This protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. SNAI2 is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Recombinant human SNAI2, fused to His-tag at N-terminus, was expressed in E.coli.

Molecular Weight: 32.4kDa (291aa)

NCBI Accession: NP_003059

UniProt: O43623