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CD207 Protein (AA 65-328) (His tag)

CD207 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN5854553
  • Target See all CD207 Proteins
    CD207 (CD207 Molecule, Langerin (CD207))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 65-328
    Origin
    • 6
    • 2
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This CD207 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    ADPPRFMGTI SDVKTNVQLL KGRVDNISTL DSEIKKNSDG MEAAGVQIQM VNESLGYVRS QFLKLKTSVE KANAQIQILT RSWEEVSTLN AQIPELKSDL EKASALNTKI RALQGSLENM SKLLKRQNDI LQVVSQGWKY FKGNFYYFSL IPKTWYSAEQ FCVSRNSHLT SVTSESEQEF LYKTAGGLIY WIGLTKAGME GDWSWVDDTP FNKVQSARFW IPGEPNNAGN NEHCGNIKAP SLQAWNDAPC DKTFLFICKR PYVPSEPHHH HHH
    Purity
    > 90 % by SDS - PAGE
    Endotoxin Level
    < 1.0 EU per 1 microgram of protein (determined by LAL method)
    Top Product
    Discover our top product CD207 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    CD207 (CD207 Molecule, Langerin (CD207))
    Alternative Name
    CD207 (CD207 Products)
    Synonyms
    CD207 Protein, CLEC4K Protein, RGD1565913 Protein, CD207 molecule Protein, CD207 antigen Protein, CD207 Protein, Cd207 Protein
    Background
    CD207, also known as C-type lectin domain family 4 member K, is a type 2 transmembrane glycoprotein. This protein is used as a marker for Langerhans cell which represent the immature dendritic cells in the epidermis. Also, it internalizes endogenous proteins such as type 1 procollagen. Internalization by Langerhans cell is thought to lead to suppression of self reactions. CD207 meditates endocytosis of non-peptide antigens containing mannose, N-acetyl glucosamine and fucose that are expressed by mycobacteria and fungae. Recombinant human CD207, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Molecular Weight
    30.9kDa (273aa) 28-40KDa (SDS-PAGE under reducing conditions.)
    NCBI Accession
    NP_056532
    UniProt
    Q9UJ71
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