IFNAR1 Protein (AA 27-429) (His tag)
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- Target See all IFNAR1 Proteins
- IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-429
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Origin
- Mouse
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This IFNAR1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ENLKPPENID VYIIDDNYTL KWSSHGESMG SVTFSAEYRT KDEAKWLKVP ECQHTTTTKC EFSLLDTNVY IKTQFRVRAE EGNSTSSWNE VDPFIPFYTA HMSPPEVRLE AEDKAILVHI SPPGQDGNMW ALEKPSFSYT IRIWQKSSSD KKTINSTYYV EKIPELLPET TYCLEVKAIH PSLKKHSNYS TVQCISTTVA NKMPVPGNLQ VDAQGKSYVL KWDYIASADV LFRAQWLPGY SKSSSGSRSD KWKPIPTCAN VQTTHCVFSQ DTVYTGTFFL HVQASEGNHT SFWSEEKFID SQKHILPPPP VITVTAMSDT LLVYVNCQDS TCDGLNYEII FWENTSNTKI SMEKDGPEFT LKNLQPLTVY CVQARVLFRA LLNKTSNFSE KLCEKTRPGS FSTLEHHHHH H
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product IFNAR1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
- Alternative Name
- Ifnar1 (IFNAR1 Products)
- Synonyms
- ifnar1 Protein, IFNAR1 Protein, CD118 Protein, Ifar Protein, Ifnar Protein, Ifrc Protein, Infar Protein, AVP Protein, IFN-alpha-REC Protein, IFNAR Protein, IFNBR Protein, IFRC Protein, IFN-R-1 Protein, interferon alpha and beta receptor subunit 1 Protein, interferon-alpha/beta receptor alpha chain-like Protein, interferon (alpha and beta) receptor 1 Protein, interferon alpha/beta receptor 1 Protein, IFNAR1 Protein, ifnar1 Protein, Ifnar1 Protein, LOC609830 Protein
- Background
- Ifnar1, also known as Interferon alpha/beta receptor 1, is a member of the class II cytokine receptor family of proteins. This protein forms one of the two chains of a receptor for interferons alpha and beta. It binds and activate of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor. Recombinant mouse Ifnar1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 46.8kDa (411aa) 40-57KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_034638
- UniProt
- P33896
- Pathways
- JAK-STAT Signaling, Hepatitis C
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