STK3 Protein (AA 1-322) (His tag)

Catalog No. ABIN5854717

Product Details

Target: STK3 (serine/threonine Kinase 3 (STK3))

Protein Type: Recombinant

Protein Characteristics: AA 1-322

Origin: Human

Source: Baculovirus infected Insect Cells

Purification tag / Conjugate: This STK3 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: ADPMEQPPAP KSKLKKLSED SLTKQPEEVF DVLEKLGEGS YGSVFKAIHK ESGQVVAIKQ VPVESDLQEI IKEISIMQQC DSPYVVKYYG SYFKNTDLWI VMEYCGAGSV SDIIRLRNKT LIEDEIATIL KSTLKGLEYL HFMRKIHRDI KAGNILLNTE GHAKLADFGV AGQLTDTMAK RNTVIGTPFW MAPEVIQEIG YNCVADIWSL GITSIEMAEG KPPYADIHPM RAIFMIPTNP PPTFRKPELW SDDFTDFVKK CLVKNPEQRA TATQLLQHPF IKNAKPVSIL RDLITEAMEI KAKRHEEQQR ELEEEEENSD EDELDHHHHH H

Purity: > 90 % by SDS - PAGE

Endotoxin Level: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: STK3 (serine/threonine Kinase 3 (STK3))

Alternative Name: STK3 (STK3 Products)

Synonyms: KRS1 Protein, MST2 Protein, 0610042I06Rik Protein, MST Protein, Mst2 Protein, Mst3 Protein, Ste20 Protein, mess1 Protein, mst2 Protein, xstk3 Protein, wu:fc19e11 Protein, zgc:55383 Protein, serine/threonine kinase 3 Protein, serine/threonine kinase 3 S homeolog Protein, serine/threonine kinase 3 (STE20 homolog, yeast) Protein, STK3 Protein, Stk3 Protein, stk3.S Protein, stk3 Protein

Background: STK3, also known as serine/threonine-protein kinase 3, is a mammalian Ste20-related protein kinases most closely related to Drosophila Hippo, a major regulator of cell proliferation and survival during development. It is a serine/threonine kinase that functions early in a pheromone responsive signal transduction cascade in yeast. It activates the human large tumor suppressor kinase Lats1. It modulates stress-induced cardiac hypertrophy. Recombinant human STK3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molecular Weight: 37.6kDa (331aa) 40-57kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_006272

UniProt: Q13188

Pathways: Tube Formation