HPGD Protein (AA 1-269) (His tag)
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- Target See all HPGD Proteins
- HPGD (Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-269
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HPGD protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMHVNGKV ALVTGAAQGI GKAFAEALLL HGAKVALVDW NLEAGVKCKA ALDEQFEPQK TLFVQCDVAD QKQLRDTFRK VVDHFGRLDI LVNNAGVNNE KNWEQTLQIN LVSVISGTYL GLDYMSKQNG GEGGIIINMS SLAGLMPVAQ QPVYCASKHG IIGFTRSAAM AANLMKSGVR LNVICPGFVD TPILESIEKE ENMGQYIEYK DQIKAMMKFY GVLHPSTIAN GLINLIEDDA LNGAIMKITA SKGIHFQDYD ISPLLVKAPL TS
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product HPGD Protein
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Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD) (AA 1-266) protein (GST tag)
HPGD Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD) (AA 1-266) protein (His tag)HPGD Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)HPGD Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl ( pH 8.0) containing 30 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- HPGD (Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))
- Alternative Name
- Hpgd (HPGD Products)
- Synonyms
- CBR Protein, SDR21C1 Protein, hCBR1 Protein, 15-PGDH Protein, PGDH Protein, PGDH1 Protein, PHOAR1 Protein, SDR36C1 Protein, MGC80546 Protein, MGC79454 Protein, AV026552 Protein, carbonyl reductase 1 Protein, 15-hydroxyprostaglandin dehydrogenase Protein, hydroxyprostaglandin dehydrogenase 15-(NAD) Protein, 15-hydroxyprostaglandin dehydrogenase L homeolog Protein, hydroxyprostaglandin dehydrogenase 15 (NAD) Protein, CBR1 Protein, HPGD Protein, hpgd.L Protein, hpgd Protein, pgdh Protein, Hpgd Protein, PTRG_03214 Protein, VDBG_09957 Protein
- Background
- Hpgd, also known as Hydroxyprostaglandin dehydrogenase, is a member of the short-chain dehydrogenases/reductases family. It metabolizes prostaglandins (PGs) to render them. Prostaglandins (PGs) play a crucial role in mediating parturition events, and their synthesis and metabolism are regulated by PGH synthase and 15-hydroxy-PG dehydrogenase (PGDH), respectively. Hpgd, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers. Recombinant mouse Hpgd protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 31.6kDa (292aa)
- NCBI Accession
- NP_032304
- UniProt
- Q8VCC1
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