SCN3B Protein (AA 23-159) (His tag)
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- Target See all SCN3B Proteins
- SCN3B (Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-159
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This SCN3B protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPFPVCVEV PSETEAVQGN PMKLRCISCM KREEVEATTV VEWFYRPEGG KDFLIYEYRN GHQEVESPFQ GRLQWNGSKD LQDVSITVLN VTLNDSGLYT CNVSREFEFE AHRPFVKTTR LIPLRVTEEA GEDFTSVVSE HHHHHH
- Purity
- > 95 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product SCN3B Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- SCN3B (Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B))
- Alternative Name
- SCN3B (SCN3B Products)
- Synonyms
- 1110001K16Rik Protein, 4833414B02Rik Protein, Scnb3 Protein, HSA243396 Protein, SCNB3 Protein, sodium voltage-gated channel beta subunit 3 Protein, sodium channel, voltage-gated, type III, beta Protein, SCN3B Protein, Scn3b Protein
- Background
- SCN3B, also known as sodium channel subunit beta-3, is an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics. It was detected in brain, heart, kidney, lung, pancreas and skeletal muscle. It is expressed in adult mammalian skeletal muscle and can functionally couple to the skeletal muscle alpha subunit, SkM1. It associates with neurofascin through their extracellular immunoglobulin-like domain. Recombinant human SCN3B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 16.8kDa (146aa) 18-28kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_060870
- UniProt
- Q9NY72
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