Chorionic Gonadotropin, beta Polypeptide 3 (CGB3) (AA 21-165) protein (His tag)
CGB3
Origin: Human
Host: Baculovirus infected Insect Cells
Recombinant
> 90 % by SDS - PAGE
SDS
1 image
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- Target See all Chorionic Gonadotropin, beta Polypeptide 3 (CGB3) products
- Chorionic Gonadotropin, beta Polypeptide 3 (CGB3)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-165
- Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- His tag
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPSKEPLRP RCRPINATLA VEKEGCPVCI TVNTTICAGY CPTMTRVLQG VLPALPQVVC NYRDVRFESI RLPGCPRGVN PVVSYAVALS CQCALCRRST TDCGGPKDHP LTCDDPRFQD SSSSKAPPPS LPSPSRLPGP SDTPILPQHH HHHH
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- Chorionic Gonadotropin, beta Polypeptide 3 (CGB3)
- Alternative Name
- CGB3 (CGB3 Products)
- Synonyms
- CGB3 Protein, CGB5 Protein, CGB7 Protein, CGB8 Protein, hCGB Protein, chorionic gonadotropin beta subunit 3 Protein, CGB3 Protein
- Background
- CGB3, also known as choriogonadotropin subunit beta, is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). It stimulates the expression of GCM1 target genes, including the fusogenic protein syncytin-1, to promote placental cell fusion. It synthesized in large quantities by the developing placenta, reaching peak concentrations in maternal blood during the late first trimester and early midtrimester of pregnancy. It is expressed exclusively by trophoblasts. It is an important biomarker in pregnancy and oncology, where it is routinely detected and quantified by specific immunoassays. Recombinant human CGB3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 16.6kDa (154aa) 18-28kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_000728
- UniProt
- P0DN86
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