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CD48 Protein (CD48) (AA 27-220) (His tag)

CD48 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN7281272
  • Target See all CD48 Proteins
    CD48
    Protein Type
    Recombinant
    Protein Characteristics
    AA 27-220
    Origin
    • 19
    • 8
    • 3
    Human
    Source
    • 17
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This CD48 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    ADPQGHLVHM TVVSGSNVTL NISESLPENY KQLTWFYTFD QKIVEWDSRK SKYFESKFKG RVRLDPQSGA LYISKVQKED NSTYIMRVLK KTGNEQEWKI KLQVLDPVPK PVIKIEKIED MDDNCYLKLS CVIPGESVNY TWYGDKRPFP KELQNSVLET TLMPHNYSRC YTCQVSNSVS SKNGTVCLSP PCTLARSHHH HHH
    Purity
    > 90 % by SDS - PAGE
    Endotoxin Level
    < 1.0 EU per 1ug of protein (determined by LAL method)
    Top Product
    Discover our top product CD48 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    CD48
    Alternative Name
    CD48 (CD48 Products)
    Synonyms
    AI449234 Protein, AW610730 Protein, BCM1 Protein, BLAST Protein, BLAST-1 Protein, BLAST1 Protein, Bcm-1 Protein, MEM-102 Protein, SLAMF2 Protein, Sgp-60 Protein, hCD48 Protein, mCD48 Protein, CD48 antigen Protein, Cd48 molecule Protein, CD48 molecule Protein, Cd48 Protein, CD48 Protein
    Background
    CD48, also known as CD48 antigen isoform 1, is a GPI-linked protein in the CD2 family of immunoglobulin superfamily molecules. This protein is competent to transduce signals and can also trigger signaling through CD2 or 2B4. CD48-CD2 interactions promote T cell activation and class switching to IgG2a in B cells. High affinity CD48-2B4 interactions can either promote or inhibit NK cell and cytotoxic T cell (CTL) activation. It expressed on NK cells is coactivating, whereas CD48 expressed on other cell types inhibits NK cell activation. Recombinant human CD48, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Molecular Weight
    23.4kDa (203aa) 28-40kDa (SDS-PAGE under reducing conditions.)
    NCBI Accession
    NP_001769
    UniProt
    P09326
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