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RAD23A Protein (AA 2-201, partial) (GST tag)

RAD23A Origin: Human Host: Escherichia coli (E. coli) Recombinant 95 % SDS, ELISA, WB
Catalog No. ABIN618825
  • Target See all RAD23A Proteins
    RAD23A (RAD23 Homolog A (RAD23A))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 2-201, partial
    Origin
    • 6
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This RAD23A protein is labelled with GST tag.
    Application
    SDS-PAGE (SDS), ELISA, Western Blotting (WB)
    Sequence
    AVTITLKTLQ QQTFKIRMEP DETVKVLKEK IEAEKGRDAF PVAGQKLIYA GKILSDDVPI RDYRIDEKNF VVVMVTKTKA GQGTSAPPEA SPTAAPESST SFPPAPTSGM SHPPPAARED KSPSEESAPT TSPESVSGSV PSSGSSGREE DAASTLVTGS EYETMLTEIM SMGYERERVV AALRASYNNP HRAVEYLLTG
    Purity
    95 %
    Top Product
    Discover our top product RAD23A Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS buffer, 20mM GSH
    Storage
    4 °C
  • Target
    RAD23A (RAD23 Homolog A (RAD23A))
    Alternative Name
    UV excision repair protein RAD23 homolog A (RAD23A Products)
    Synonyms
    rad23a Protein, wu:fe11h06 Protein, zgc:92001 Protein, RAD23A Protein, HHR23A Protein, HR23A Protein, 2310040P19Rik Protein, AL024030 Protein, mHR23A Protein, RAD23 homolog A, nucleotide excision repair protein a Protein, RAD23 homolog A, nucleotide excision repair protein Protein, rad23aa Protein, RAD23A Protein, Rad23a Protein
    Background
    Background: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. Ref.6 Ref.9 Ref.10 Ref.11 Ref.20 Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair (GG-NER) by association with XPC. In vitro, the XPC:RAD23A dimer has NER activity. Can stabilize XPC. Ref.6 Ref.9 Ref.10 Ref.11 Ref.20 Involved in vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages. Required for the association of HIV-1 vpr with the host proteasome. Synonyms: Short name=HR23A Short name=hHR23A
    Molecular Weight
    48.8 kD
    NCBI Accession
    NM_005053
    UniProt
    P54725
    Pathways
    DNA Damage Repair
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