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CD38 Protein (AA 44-301) (His tag)

Origin: Cynomolgus Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN6253545
  • Target See all CD38 Proteins
    CD38
    Protein Type
    Recombinant
    Protein Characteristics
    AA 44-301
    Origin
    • 25
    • 10
    • 5
    • 3
    • 1
    Cynomolgus
    Source
    • 18
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD38 protein is labelled with His tag.
    Sequence
    AA 44-301
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CD38 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    50 mM MES, 100 mM NaCl, pH 6.5
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
  • Target
    CD38
    Abstract
    CD38 Products
    Synonyms
    T10 Protein, Cd38-rs1 Protein, cd38 Protein, ADPRC 1 Protein, cADPr hydrolase 1 Protein, CD38 molecule Protein, CD38 antigen Protein, CD38 molecule L homeolog Protein, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Protein, CD38 Protein, Cd38 Protein, cd38.L Protein
    Background
    CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
    Molecular Weight
    31.8 kDa
    NCBI Accession
    NP_001274206
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