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Prolactin Protein (PRL) (AA 29-227) (Fc Tag)

PRL Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN6253591
  • Target See all Prolactin (PRL) Proteins
    Prolactin (PRL)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 29-227
    Origin
    • 14
    • 13
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 31
    • 29
    • 4
    • 4
    • 3
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Prolactin protein is labelled with Fc Tag.
    Sequence
    AA 29-227
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 0.1 EU per μg by the LAL method.
    Top Product
    Discover our top product PRL Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
  • Target
    Prolactin (PRL)
    Alternative Name
    Prolactin (PRL Products)
    Synonyms
    PRL Protein, prolactin Protein, PRLB Protein, PRLSD1 Protein, Prl1a1 Protein, Prol Protein, RATPRLSD1 Protein, RNPROL Protein, AV290867 Protein, prl Protein, prolactin Protein, prolactin, gene 2 L homeolog Protein, PROLACTIN protein Protein, prolactin-like Protein, PRL Protein, prl.2.L Protein, Prl Protein, LOC100136792 Protein, LOC100136580 Protein, PROLACTIN Protein, LOC101843376 Protein
    Background
    Prolactin (gene name PRL) is a secreted neuroendocrine pituitary hormone that acts primarily on the mammary gland to promote lactation, but has pleiotropic effects in both males and females. Prolactin is synthesized as a prohormone. Following cleavage of the signal peptide, the length of the mature hormone is between 194 and 199 amino acids, depending on species. Hormone structure is stabilized by three intramolecular disulfide bonds. Excessive secretion of prolactin - hyperprolactinemia - is a relative common disorder in humans. This condition has numerous causes, including prolactin-secreting tumors and therapy with certain drugs. The prolactin receptor (gene name PRLR) is a transmembrane type I glycoprotein that belongs to the cytokine hematopoietic receptor family. Expression of the prolactin receptor is widespread. Each prolactin molecule is thought to bind two receptor molecules
    Molecular Weight
    49.8 kDa
    NCBI Accession
    NP_000939
    Pathways
    JAK-STAT Signaling, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Protein targeting to Nucleus
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