ABI3 Protein
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- Target See all ABI3 Proteins
- ABI3 (ABI Family, Member 3 (ABI3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product ABI3 Protein
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- Comment
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Synonyms: ABI family, member 3, NESH, SSH3BP3
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- ABI3 (ABI Family, Member 3 (ABI3))
- Alternative Name
- ABI3 (ABI3 Products)
- Synonyms
- NESH Protein, SSH3BP3 Protein, 2210414K06Rik Protein, AI987680 Protein, ABI family member 3 Protein, ABI family, member 3 Protein, ABI gene family, member 3 Protein, ABI3 Protein, Abi3 Protein
- Background
- ABI3, also as known as ABI gene family member 3, belongs to the ABI family. This protein is a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain. The Abi family members are thought to negatively regulate cell growth and transformation, including cellular transformation through v-Abl as well as mediate cell motility by regulating actin polymerization in lamellipodia and filopodia. ABI3 inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase.
- Molecular Weight
- 41.4 kDa (389aa)
- NCBI Accession
- NP_057512
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