DTD1 Protein (His tag)
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- Target See all DTD1 Proteins
- DTD1 (D-Tyrosyl-tRNA Deacylase 1 Homolog (S. Cerevisiae) (DTD1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DTD1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product DTD1 Protein
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- Comment
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Synonyms: D-tyrosyl-tRNA deacylase 1, bA379J5.3, bA555E18.1, C20orf88, DUEB, HARS2, pqn-68
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- DTD1 (D-Tyrosyl-tRNA Deacylase 1 Homolog (S. Cerevisiae) (DTD1))
- Alternative Name
- DTD1 (DTD1 Products)
- Synonyms
- 0610006H08Rik Protein, Hars2 Protein, C20orf88 Protein, DUEB Protein, HARS2 Protein, bA379J5.3 Protein, bA555E18.1 Protein, pqn-68 Protein, hars2 Protein, zgc:92657 Protein, D-tyrosyl-tRNA deacylase 1 Protein, Dtd1 Protein, DTD1 Protein, dtd1 Protein
- Background
- DTD1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). It could be a defense mechanism against a harmful effect of D-tyrosine. DTD1 may be a risk factor for aspirin-intolerant asthma (AIA) by catalyzing the hydrolysis of D-tryptophan and interacting with the tyrosyl-tRNA synthetase (tyrRS) enzyme, which promotes a pro-inflammatory phenotype. This protein is localize to the DUE(DNA unwinding element )s of active replication origins. Recombinant human DTD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 25.9kDa (232aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_543010
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