RAMP3 Protein (His tag)

Catalog No. ABIN6387128

Product Details

Target: RAMP3 (Receptor (G Protein-Coupled) Activity Modifying Protein 3 (RAMP3))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This RAMP3 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Purity: > 90 % by SDS - PAGE

Application Details

Comment:

Synonyms: Receptor activity modifying protein 3, Receptor (calcitonin) activity modifying protein 3

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1 M NaCl

Storage: 4 °C

Storage Comment: Avoid repeated freezing and thawing cycles.

Target Details

Target: RAMP3 (Receptor (G Protein-Coupled) Activity Modifying Protein 3 (RAMP3))

Alternative Name: RAMP3 (RAMP3 Products)

Synonyms: RAMP3 Protein, ramp3 Protein, AI850306 Protein, receptor activity modifying protein 3 Protein, receptor (G protein-coupled) activity modifying protein 3 Protein, Receptor activity-modifying protein 3 Protein, receptor (calcitonin) activity modifying protein 3 Protein, RAMP3 Protein, ramp3 Protein, Ramp3 Protein

Background: RAMP3, also known as receptor activity modifying protein 3, is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). It is required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR can function as either a calcitonin gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor. Recombinant human RAMP3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 13.0 kDa(116aa) confirmed by MALDI-TOF

NCBI Accession: NP_005847

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling