AIDA Protein (His tag)

Catalog No. ABIN1098551

Product Details

Target: AIDA (Axin Interactor, Dorsalization Associated (AIDA))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This AIDA protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Purity: > 90 % by SDS - PAGE

Application Details

Comment:

Synonyms: Axin interactor, dorsalization-associated, C1orf80, RP11-378J18.7

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.2 M NaCl,1 MM DTT

Storage: 4 °C

Storage Comment: Avoid repeated freezing and thawing cycles.

Target Details

Target: AIDA (Axin Interactor, Dorsalization Associated (AIDA))

Alternative Name: AIDA (AIDA Products)

Synonyms: C1orf80 Protein, RP11-378J18.7 Protein, 2610208M17Rik Protein, BC004835 Protein, zgc:73327 Protein, AIDA Protein, axin interactor, dorsalization associated Protein, axin interactor, dorsalization associated L homeolog Protein, axin interactor, dorsalization associated S homeolog Protein, AIDA Protein, Aida Protein, aida Protein, aida.L Protein, aida.S Protein

Background: AIDA acts as a ventralizing factor during embryogenesis. This protein inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling. Recombinant human AIDA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 37.4kDa(329aa) confirmed by MALDI-TOF

NCBI Accession: NP_073742