BIN2 Protein (AA 1-597) (His tag)
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- Target See all BIN2 Proteins
- BIN2 (Bridging Integrator 2 (BIN2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-597
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This BIN2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPMRGMPGA RTSSSGASEN HRARGQGGGP QGVGRMAEGK AGGAAGLFAK QVQKKFSRAQ EKVLQKLGKA VETKDERFEQ SASNFYQQQA EGHKLYKDLK NFLSAVKVMH ESSKRVSETL QEIYSSEWDG HEELKAIVWN NDLLWEDYEE KLADQAVRTM EIYVAQFSEI KERIAKRGRK LVDYDSARHH LEAVQNAKKK DEAKTAKAEE EFNKAQTVFE DLNQELLEEL PILYNSRIGC YVTIFQNISN LRDVFYREMS KLNHNLYEVM SKLEKQHSNK VFVVKGLSSS SRRSLVISPP VRTATVSSPL TSPTSPSTLS LKSESESVSA TEDLAPDAAQ GEDNSEIKEL LEEEEIEKEG SEASSSEEDE PLPACNGPAQ AQPSPTTERA KSQEEVLPSS TTPSPGGALS PSGQPSSSAT EVVLRTRTAS EGSEQPKKRA SIQRTSAPPS RPPPPRATAS PRPSSGNIPS SPTASGGGSP TSPRASLGTG TASPRTSLEV SPNPEPPEKP VRTPEAKENE NIHNQNPEEL CTSPTLMTSQ VASEPGEAKK MEDKEKDNKL ISANSSEGQD QLQVSMVPEN NNLTAPEPQE EVSTSENPQL HHHHHH
- Purity
- > 80 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product BIN2 Protein
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Bridging Integrator 2 (BIN2) (AA 1-489) protein (Strep Tag)
Crystallography grade BIN2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Bridging Integrator 2 (BIN2) (AA 1-565) protein (Strep Tag)Crystallography grade BIN2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Bridging Integrator 2 (BIN2) protein (Myc-DYKDDDDK Tag)BIN2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 20 % glycerol, 1 mM DTT, 0.1 mM PMSF.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- BIN2 (Bridging Integrator 2 (BIN2))
- Alternative Name
- BIN2 (BIN2 Products)
- Synonyms
- BRAP-1 Protein, BIN2 Protein, bin2l Protein, wu:fi05e01 Protein, zgc:55758 Protein, bridging integrator 2 Protein, bridging integrator 2b Protein, BIN2 Protein, Bin2 Protein, bin2b Protein
- Background
- BIN2, also known as bridging integrator 2 isoform1, is a cytoplasmic protein. It contains one BAR domain and Interacts with BIN1. This protein is highly expressed in some hematopoietic tissues, including peripheral blood, thymus, colon and placenta. It Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton and also modulates membrane curvature and mediates membrane tubulation. Recombinant human BIN2 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 66.1kDa (606aa) 70-100KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_057377
- UniProt
- Q9UBW5
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