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BIN2 Protein (His tag)

BIN2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318210
  • Target See all BIN2 Proteins
    BIN2 (Bridging Integrator 2 (BIN2))
    Protein Type
    Recombinant
    Origin
    • 4
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This BIN2 protein is labelled with His tag.
    Purpose
    Recombinant Human Bridging Integrator 2/BIN2 Protein (His Tag)
    Sequence
    Met 1-Asn244
    Characteristics
    Recombinant Human Bridging Integrator 2 is produced by our E.coli expression system and the target gene encoding Met1-Asn244 is expressed with a 6His tag at the N-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product BIN2 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    BIN2 (Bridging Integrator 2 (BIN2))
    Alternative Name
    Bridging Integrator 2/BIN2 (BIN2 Products)
    Synonyms
    BRAP-1 Protein, BIN2 Protein, bin2l Protein, wu:fi05e01 Protein, zgc:55758 Protein, bridging integrator 2 Protein, bridging integrator 2b Protein, BIN2 Protein, Bin2 Protein, bin2b Protein
    Background

    Background: Bridging Integrator 2 (BIN2) is a cytoplasmic protein. BIN2 contains one BAR domain and Interacts with BIN1. BIN2 is highly expressed in some hematopoietic tissues, including peripheral blood, thymus, colon and placenta. BIN2 is an Arabidopsis GSK3-like kinase that negatively regulates brassinosteroid (BR) signaling. Genetic studies show that BIN2 is inhibited in response to BR perception at the cell surface to relieve its inhibitory effects on downstream targets.

    Synonym: Bridging Integrator 2, Breast Cancer-Associated Protein 1, BIN2, BRAP1

    Molecular Weight
    30.6 kDa
    UniProt
    Q9UBW5
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