PKM2 Protein (AA 1-531) (His tag)
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- Target See all PKM2 Proteins
- PKM2 (Pyruvate Kinase M2 (PKM2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-531
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PKM2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- PKM2, 1-531aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product PKM2 Protein
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Pyruvate Kinase M2 (PKM2) (AA 1-531) protein (GST tag)
PKM2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Pyruvate Kinase M2 (PKM2) (AA 436-531) protein (GST tag)PKM2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Pyruvate Kinase M2 (PKM2) (AA 1-531) protein (His tag)PKM2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Pyruvate Kinase M2 (PKM2) (AA 1-531) protein (His tag)PKM2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
- Storage
- 4 °C
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- Target
- PKM2 (Pyruvate Kinase M2 (PKM2))
- Alternative Name
- PKM2 (PKM2 Products)
- Synonyms
- CTHBP Protein, OIP3 Protein, PK3 Protein, PKM2 Protein, TCB Protein, THBP1 Protein, AA414905 Protein, AL024370 Protein, AL024424 Protein, Pk-2 Protein, Pk-3 Protein, Pk3 Protein, Pkm2 Protein, PKM12 Protein, PKM Protein, pyruvate kinase M1/2 Protein, pyruvate kinase, muscle Protein, PKM Protein, Pkm Protein
- Background
- PKM2 is an isoenzyme of the glycolytic enzyme pyruvate kinase. This protein catalyzes the production of pyruvate and ATP from phosphoenolpyruvate. PKM2 interacting with Opa proteins, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, is required for bacterial pathogenesis. It is specifically expressed at high levels in tumor cells, and can be measured in plasma of patients with advanced breast cancer. Recombinant human PKM2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: CTHBP, THBP1, p58, M2-PK, Tumor M2-PK, PK2, PK3, PKM, pyruvate kinase, muscle isoform M2 OIP3, PKM, TCB, OPA interacting protein 3, PKM2, Cytosolic thyroid hormone binding protein, Pyruvate kinase 2/3, Pyruvate kinase isozymes M1/M2, Pyruvate kinase muscle, Thyroid hormone binding protein cytosolic. NCBI no.: NP_002645
- Molecular Weight
- 60.1 kDa (551aa)
- Pathways
- Warburg Effect
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