CACYBP Protein (AA 1-185) (His tag)
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- Target See all CACYBP Proteins
- CACYBP (Calcyclin Binding Protein (CACYBP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-185
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CACYBP protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- CACYBP, 1-185aa, Human, His tag, E.coli
- Purity
- > 85 % by SDS-PAGE
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.
- Storage
- 4 °C
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- Target
- CACYBP (Calcyclin Binding Protein (CACYBP))
- Alternative Name
- CACYBP (CACYBP Products)
- Synonyms
- zgc:76993 Protein, CACYBP Protein, sip Protein, gig5 Protein, pnas-107 Protein, s100a6bp Protein, T1P2.12 Protein, T1P2_12 Protein, GIG5 Protein, RP1-102G20.6 Protein, S100A6BP Protein, SIP Protein, calcyclin binding protein Protein, calcyclin binding protein, putative Protein, Calcyclin binding protein, putative Protein, SGS domain-containing protein Protein, calcyclin binding protein L homeolog Protein, cacybp Protein, CACYBP Protein, PB000926.02.0 Protein, PCHAS_145490 Protein, PVX_100855 Protein, PKH_145680 Protein, AT1G30070 Protein, cacybp.L Protein, Cacybp Protein
- Background
- CACYBP is primarily a nuclear protein that contains one CS domain and one SGS domain. It is believed to be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It most likely serves as a molecular bridge in Ubiquitin E3 complexes. It also participates in the Ubiquitin-mediated degradation of beta-catenin. CACYBP is thought to be a potential inhibitor of cell growth and invasion in the gastric cancer cell through its effects on beta-catenin protein expression and transcriptional activation of TCF/LEF. Recombinant human CACYBP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: GIG5, PNAS-107, RP1-102G20.6, S100A6BP, SIP, Clcyclin-binding protein CACYBP, Calcyclin binding protein, GIG 5, Growth inhibiting gene 5, Growth inhibiting gene 5 protein, hCacyBP, MGC87971, PNAS 107, PNAS107, RP1 102G20.6, S100A6 binding protein. NCBI no.: NP_001007215
- Molecular Weight
- 23.4 kDa (205aa), confirmed by MALDI-TOF
- Pathways
- Response to Growth Hormone Stimulus
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