Transgelin Protein (TAGLN) (AA 1-201) (His tag)
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- Target See all Transgelin (TAGLN) Proteins
- Transgelin (TAGLN)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-201
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Transgelin protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- TAGLN, 1-201aa, Human, His tag, E.coli
- Purity
- > 85 % by SDS-PAGE
- Top Product
- Discover our top product TAGLN Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 20% glycerol 1mM DTT
- Storage
- 4 °C
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- Target
- Transgelin (TAGLN)
- Alternative Name
- TAGLN (TAGLN Products)
- Synonyms
- MGC68550 Protein, sm22 Protein, smcc Protein, tagln1 Protein, ws3-10 Protein, MGC107855 Protein, SM22 Protein, SMCC Protein, TAGLN1 Protein, WS3-10 Protein, Sm22 Protein, Sm22a Protein, Ws310 Protein, SM22A Protein, zgc:153186 Protein, transgelin L homeolog Protein, transgelin Protein, tagln.L Protein, tagln Protein, LOC732906 Protein, TAGLN Protein, tagl Protein, LOC100009332 Protein, Tagln Protein
- Background
- TAGLN is a transformation and shape-change sensitive actin cross-linking/gelling protein that belongs to the calponin family. This protein is expressed abundantly in fibroblasts and smooth muscle. It is involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence. During embryogenesis, TAGLN is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. It is downregulated in several transformed cell lines, indicating that a reduction of TAGLN expression may be an early indicator of the onset of transformation. Recombinant human TAGLN protein, fused to his-tag at N-terminus was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: SM22, SMCC, TAGLN1, WS3-10, Transgelin, SM 22, SM22 alpha, SMCC, Smooth muscle protein 22-alpha, WS3 10. NCBI no.: NP_001001522
- Molecular Weight
- 24.8 kDa (221aa) confirmed by MALDI-TOF
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