UROD Protein (AA 1-367) (His tag)
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- Target See all UROD Proteins
- UROD (Uroporphyrinogen Decarboxylase (UROD))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-367
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This UROD protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- UROD, 1-367aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product UROD Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 20% glycerol 1mM DTT, 0.1M NaCl, and 1mM EDTA.
- Storage
- 4 °C
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- Target
- UROD (Uroporphyrinogen Decarboxylase (UROD))
- Alternative Name
- UROD (UROD Products)
- Synonyms
- UROD Protein, pct Protein, wu:fc43e09 Protein, PCT Protein, UPD Protein, AI323803 Protein, Uro-d Protein, porphyrinogen carboxy-lyase Protein, uroporphyrinogen decarboxylase Protein, Uroporphyrinogen decarboxylase UroD Protein, Uroporphyrinogen decarboxylase Protein, UROD Protein, urod Protein, hemE Protein, uroD Protein, Cpin_6502 Protein, Rmar_1187 Protein, LOC5568261 Protein, Mrub_1403 Protein, Arnit_2230 Protein, Ndas_2830 Protein, Mesil_2989 Protein, Trad_0222 Protein, Weevi_0432 Protein, Hipma_1229 Protein, Fluta_0529 Protein, Marky_1143 Protein, Halhy_5610 Protein, Mesop_0899 Protein, Ccan_20670 Protein, Urod Protein
- Background
- UROD is the fifth enzyme in the human heme biosynthetic pathway and is responsible for the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are responsible for three autosomal disorders in humans: familial porphyria cutanea tarda (f-PCT), sporadic porphyria cutanea tarda (s-PCT) and hepatoerythropoietic porphyria (HEP). Recombinant human UROD protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: PCT, Uroporphyrinogen decarboxylase, UPD, URO D, URO-D. NCBI no.: AAH01778
- Molecular Weight
- 43.0 kDa (387aa) confirmed by MALDI-TOF
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