GMDS Protein (AA 1-372) (His tag)
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- Target See all GMDS Proteins
- GMDS (GDP-Mannose 4,6-Dehydratase (GMDS))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-372
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GMDS protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- GMDS, 1-372aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product GMDS Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 30% glycerol, 0.1M NaCl,1mM DTT, 0.1mM PMSF
- Storage
- 4 °C
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- Target
- GMDS (GDP-Mannose 4,6-Dehydratase (GMDS))
- Alternative Name
- GMDS (GMDS Products)
- Synonyms
- BC031788 Protein, C87208 Protein, GMD Protein, SDR3E1 Protein, GDP-mannose 4, 6-dehydratase Protein, GDP-mannose 4,6-dehydratase Protein, Gmds Protein, GMDS Protein
- Background
- GMDS, also known as SDR3E1, belongs to the GDP-mannose 4,6-dehydratase family. This protein utilizes NADP as a cofactor to catalyze the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose. Mutations in the gene encoding GMDS are involved in resistance to TRAIL (tumor necrosis factor-related apoptosis-inducing ligand)-induced apoptosis. Recombinant human GMDS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: GDP-mannose 4,6 dehydratase, GMD, SDR3E1. NCBI no.: NP_001491
- Molecular Weight
- 44.1 kDa (392aa), confirmed by MALDI-TOF
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