VTA1 Protein (AA 1-307) (His tag)
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- Target See all VTA1 Proteins
- VTA1 (Vps20-Associated 1 Homolog (VTA1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-307
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This VTA1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- VTA1, 1-307aa , Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product VTA1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 200mM NaCl
- Storage
- 4 °C
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- Target
- VTA1 (Vps20-Associated 1 Homolog (VTA1))
- Alternative Name
- VTA1 (VTA1 Products)
- Synonyms
- C6orf55 Protein, DRG-1 Protein, DRG1 Protein, LIP5 Protein, My012 Protein, SBP1 Protein, 1110001D18Rik Protein, 1110059P08Rik Protein, AU040813 Protein, C85340 Protein, Lip5 Protein, RGD1305031 Protein, Vps20-associated 1 homolog Protein, vesicle trafficking 1 Protein, vesicle (multivesicular body) trafficking 1 Protein, Vta1 Protein, VTA1 Protein
- Background
- VTA1 (Vps20-associated 1 homolog), also known as LIP5 (LYST-interacting protein 5), DRG1 (Dopamine-responsive protein DRG-1), SBP1 (SKD1 bindingprotein 1), belongs to the VTA1 family. This protein Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Also, VTA1 is known to interact with CHMP1B, CHMP2A, CHMP5, VPS4B, KIAA0174 (IST1) and possibly CHMP3. Recombinant human VTA1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: vacuolar protein sorting-associated protein VTA1 homolog, DRG-1, DRG1, LIP5, SBP1. NCBI no.: NP_057569
- Molecular Weight
- 36.5kDa (331aa), confirmed by MALDI-TOF
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