AKR7A3 Protein (AA 1-331) (His tag)
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- Target See all AKR7A3 Proteins
- AKR7A3 (Aldo-Keto Reductase Family 7, Member A3 (Aflatoxin Aldehyde Reductase) (AKR7A3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-331
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This AKR7A3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- AKR7A3, 1-331aa, Human, His tag, E. coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product AKR7A3 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 100mM NaCl, 10% glycerol
- Storage
- 4 °C
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- Target
- AKR7A3 (Aldo-Keto Reductase Family 7, Member A3 (Aflatoxin Aldehyde Reductase) (AKR7A3))
- Alternative Name
- AKR7A3 (AKR7A3 Products)
- Synonyms
- AFAR2 Protein, fd56g11 Protein, wu:fd56g11 Protein, zgc:92502 Protein, AKR7A2 Protein, Afar Protein, Akr7a1 Protein, aldo-keto reductase family 7 member A3 Protein, aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) Protein, aflatoxin B1 aldehyde reductase member 3 Protein, AKR7A3 Protein, akr7a3 Protein, LOC788425 Protein, Akr7a3 Protein
- Background
- Aldo-keto reductase family 7, member A 3, also known as AKR7A3, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member includes a number of related monomeric NADPH-dependent oxidoreductases, such as aldehyde reductase, aldose reductase, prostaglandin F synthase, xylose reductase, rho crystallin, and many others. AKR7A3 is involved in the detoxification of aldehydes and ketones. The activity of AKR7A3 may detoxify the aflatoxin B1 (AFB1) dialdehyde, which reacts with proteins, and thereby inhibits AFB 1 induced toxicity. Recombinant human AKR7A3, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Aflatoxin B1 aldehyde reductase member 3, AFB1 aldehyde reductase 2(AFAR2), Aldo-keto reductase family 7, member A 3 AFAR 2, AFAR2, AFB1 AR 2, Aflatoxin aldehyde reductase, Aflatoxin B1 aldehyde reductase 2, Aflatoxin B1 aldehyde reductase member 3, Aldo keto reductase family 7 member A3, OTTHUMP00000002623. NCBI no.: AAH25709
- Molecular Weight
- 41.6 kDa (370aa), confirmed by MALDI-TOF.
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