TXNL1 Protein (AA 1-289) (His tag)
Quick Overview for TXNL1 Protein (AA 1-289) (His tag) (ABIN667868)
Target
See all TXNL1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-289
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Purification tag / Conjugate
- This TXNL1 protein is labelled with His tag.
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Sequence
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MVGVKPVGSD PDFQPELSGA GSRLAVVKFT MRGCGPCLRI APAFSSMSNK YPQAVFLEVD VHQCQGTAAT NNISATPTFL FFRNKVRIDQ YQGADAVGLE EKIKQHLEND PGSNEDTDIP KGYMDLMPFI NKAGCECLNE SDEHGFDNCL RKDTTFLESD CDEQLLITVA FNQPVKLYSM KFQGPDNGQG PKYVKIFINL PRSMDFEEAE RSEPTQALEL TEDDIKEDGI VPLRYVKFQN VNSVTIFVQS NQGEEETTRI SYFTFIGTPV QATNMNDFKR VVGKKGESH -
Characteristics
- TXNL1, 1-289aa, Human, His tag, E.coli
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Purification
- > 95% by SDS-PAGE
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Thioredoxin-Like 1 (TXNL1) (AA 1-289) protein (His-IF2DI Tag)
TXNL1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Thioredoxin-Like 1 (TXNL1) (AA 2-289) protein (His-SUMO Tag)TXNL1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Thioredoxin-Like 1 (TXNL1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)TXNL1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- 20 mM Tris-HCl buffer ( pH 8.0) containing 0.2M NaCl, 5 mM DTT, 20 % glycerol
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- TXNL1 (Thioredoxin-Like 1 (TXNL1))
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Alternative Name
- TXNL1
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Background
- TXNL1, also known as TRP32, TXL or TXL-1, is a cytoplasmic protein that participates in endocytotic signaling pathways and acts as a redox sensor. Expressed throughout the body, TXNL1 functions to couple oxidative stress to endocytosis, thereby regulating the GDI. Additionally, overexpression of TXNL1 inhibits cell proliferation by predisposing the cell to G0/G1 arrest, suggesting that TXNL1 also functions as a transcriptional repressor. Recombinant human TXNL1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
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Molecular Weight
- 34.4 kDa (309aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_004777
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Pathways
- Cell RedoxHomeostasis
Target
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