DDIT4 Protein (AA 1-232) (His tag)
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- Target See all DDIT4 Proteins
- DDIT4 (DNA-Damage-Inducible Transcript 4 (DDIT4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-232
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DDIT4 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- DDIT4, 1-232aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product DDIT4 Protein
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DNA-Damage-Inducible Transcript 4 (DDIT4) (AA 1-232) protein (GST tag)
DDIT4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
DNA-Damage-Inducible Transcript 4 (DDIT4) (AA 1-99) protein (GST tag)DDIT4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
DNA-Damage-Inducible Transcript 4 (DDIT4) (AA 1-232) protein (Strep Tag)Crystallography grade DDIT4 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
DNA-Damage-Inducible Transcript 4 (DDIT4) (AA 1-229) protein (Strep Tag)Crystallography grade DDIT4 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
DNA-Damage-Inducible Transcript 4 (DDIT4) protein (Myc-DYKDDDDK Tag)DDIT4 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 1mM EDTA, 30% glycerol
- Storage
- 4 °C
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- Target
- DDIT4 (DNA-Damage-Inducible Transcript 4 (DDIT4))
- Alternative Name
- DDIT4 (DDIT4 Products)
- Synonyms
- redd1 Protein, Dig2 Protein, REDD-1 Protein, REDD1 Protein, 5830413E08Rik Protein, AA415483 Protein, Rtp801 Protein, dig2 Protein, rtp801 Protein, sb:cb821 Protein, zgc:64114 Protein, DNA damage inducible transcript 4 Protein, DNA-damage-inducible transcript 4 Protein, DNA damage inducible transcript 4 S homeolog Protein, ddit4 Protein, DDIT4 Protein, Ddit4 Protein, ddit4.S Protein
- Background
- DDIT4, also known as Dig2 or REDD1, is thought to have function in the regulation of reactive oxygen species. In response to stress due to DNA damage and glucocorticoid treatment, DDIT4 is upregulated at the transcriptional level. DDIT4 negatively regulates the mammalian target of Rapamycin, a serine/threonine kinase often referred to as mTOR. It is crucial in the coupling of extra- and intracellular cues to mTOR regulation. Recombinant human DDIT4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DNA damage-inducible transcript 4 protein, Dig2, FLJ20500, REDD1, RP11-442H21.1, RTP801. NCBI no.: NP_061931
- Molecular Weight
- 27.5 kDa (252aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
- Pathways
- Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process
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