RNMT Protein (AA 1-476) (His tag)
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- Target See all RNMT Proteins
- RNMT (RNA Guanine-7 Methyltransferase (RNMT))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-476
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RNMT protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- RNMT, 1-476aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product RNMT Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 100mM NaCl
- Storage
- 4 °C
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- Target
- RNMT (RNA Guanine-7 Methyltransferase (RNMT))
- Alternative Name
- RNMT (RNMT Products)
- Synonyms
- xCMT1 Protein, MET Protein, RG7MT1 Protein, hCMT1c Protein, 2610002P10Rik Protein, AI848273 Protein, Rg7mt1 Protein, mKIAA0398 Protein, rnmt Protein, im:6910566 Protein, wu:fi09c12 Protein, RNA (guanine-7-) methyltransferase L homeolog Protein, RNA guanine-7 methyltransferase Protein, RNA (guanine-7-) methyltransferase Protein, rnmt.L Protein, RNMT Protein, Rnmt Protein, rnmt Protein
- Background
- RNMT (mRNA cap guanine-N7 methyltransferase), also known as MET, RG7MT1 or hCMT1c, is a widely expressed nuclear protein that belongs to the mRNA cap methyltransferase family. Cap-dependent mRNA translation requires the methylation of the mRNA guanosine cap by RNMT. RNMT catalyzes the transfer of a methyl group from AdoMet (S-adenosylmethionine) to the GpppN end of the growing mRNA at the N-7 position, thereby producing AdoHyc (S-adenosylhomocysteine) and m7GpppN terminated RNA. Recombinant human RNMT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: mRNA cap guanine-N7 methyltransferase, MET, RG7MT1, DKFZp686H1252, EC 2.1.1.56, hcm1p, hCMT1, HCMT1a, hCMT1c, hMet, hypothetical protein KIAA0396, KIAA0398, MET, mRNA (guanine 7)methyltransferase, mRNA (guanine N(7)) methyltransferase, mRNA cap methyltransferase, OTTHUMP00000162509, RNA guanine 7 methyltransferase, RNA guanine-7-methyltransferase, RNMT. NCBI no.: NP_003790
- Molecular Weight
- 57.0kDa (496aa)
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