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RNMT Protein (AA 1-476) (His tag)

RNMT Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN7279447
  • Target See all RNMT Proteins
    RNMT (RNA Guanine-7 Methyltransferase (RNMT))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-476
    Origin
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This RNMT protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    RNMT, 1-476aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product RNMT Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 100mM NaCl
    Storage
    4 °C
  • Target
    RNMT (RNA Guanine-7 Methyltransferase (RNMT))
    Alternative Name
    RNMT (RNMT Products)
    Synonyms
    xCMT1 Protein, MET Protein, RG7MT1 Protein, hCMT1c Protein, 2610002P10Rik Protein, AI848273 Protein, Rg7mt1 Protein, mKIAA0398 Protein, rnmt Protein, im:6910566 Protein, wu:fi09c12 Protein, RNA (guanine-7-) methyltransferase L homeolog Protein, RNA guanine-7 methyltransferase Protein, RNA (guanine-7-) methyltransferase Protein, rnmt.L Protein, RNMT Protein, Rnmt Protein, rnmt Protein
    Background
    RNMT (mRNA cap guanine-N7 methyltransferase), also known as MET, RG7MT1 or hCMT1c, is a widely expressed nuclear protein that belongs to the mRNA cap methyltransferase family. Cap-dependent mRNA translation requires the methylation of the mRNA guanosine cap by RNMT. RNMT catalyzes the transfer of a methyl group from AdoMet (S-adenosylmethionine) to the GpppN end of the growing mRNA at the N-7 position, thereby producing AdoHyc (S-adenosylhomocysteine) and m7GpppN terminated RNA. Recombinant human RNMT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: mRNA cap guanine-N7 methyltransferase, MET, RG7MT1, DKFZp686H1252, EC 2.1.1.56, hcm1p, hCMT1, HCMT1a, hCMT1c, hMet, hypothetical protein KIAA0396, KIAA0398, MET, mRNA (guanine 7)methyltransferase, mRNA (guanine N(7)) methyltransferase, mRNA cap methyltransferase, OTTHUMP00000162509, RNA guanine 7 methyltransferase, RNA guanine-7-methyltransferase, RNMT. NCBI no.: NP_003790
    Molecular Weight
    57.0kDa (496aa)
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