SARS-CoV-2 Spike S1 Protein (mFc Tag)
Quick Overview for SARS-CoV-2 Spike S1 Protein (mFc Tag) (ABIN6952625)
Target
See all SARS-CoV-2 Spike S1 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This SARS-CoV-2 Spike S1 protein is labelled with mFc Tag.
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Purpose
- SARS-CoV-2 (COVID-19) S1 protein, Mouse IgG2a Fc Tag
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Sequence
- AA 16-685
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Characteristics
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SARS-CoV-2 S1 protein, Mouse IgG2a Fc Tag is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1). Predicted N-terminus: Val 16
This protein carries a mouse IgG2a Fc tag at the C-terminus. -
Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Handling Advice
- Please avoid repeated freeze-thaw cycles.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
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For long term storage, the product should be stored at lyophilized state at -20°C or lower.
This product is stable after storage at:
4-8°C for 12 months in lyophilized state,
-70°C for 3 years under sterile conditions after reconstitution.
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- SARS-CoV-2 Spike S1
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Target Type
- Viral Protein
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Background
- It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
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Molecular Weight
- 101.9 kDa
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Gene ID
- 43740568
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UniProt
- P0DTC2
Target
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