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Claudin 6 Protein (CLDN6) (AA 1-4) (mFc Tag)

CLDN6 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN6961123
  • Target See all Claudin 6 (CLDN6) Proteins
    Claudin 6 (CLDN6)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-4
    Origin
    • 14
    • 2
    • 1
    Human
    Source
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Claudin 6 protein is labelled with mFc Tag.
    Purpose
    Recombinant human CLDN6 Protein with C-terminal mouse Fc Tag
    Specificity
    CLDN6 (Met1-Ala4) (Gln57-Gln78) (Arg145-Arg158) mFc (Pro99-Lys330)
    Characteristics
    Extracellular Domain Protein
    Purification
    Purified from cell culture supernatant by affinity chromatography
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product CLDN6 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    Claudin 6 (CLDN6)
    Alternative Name
    CLDN6 (CLDN6 Products)
    Synonyms
    cldn4l2 Protein, cldn6 Protein, CLDN6 Protein, AL024037 Protein, claudin 6, gene 1 L homeolog Protein, claudin 6 Protein, cldn6.1.L Protein, CLDN6 Protein, Cldn6 Protein
    Background
    Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010]
    Molecular Weight
    predicted molecular mass of 31.6 kDa after removal of the signal peptide.
    Gene ID
    9074
    UniProt
    P56747
    Pathways
    Hepatitis C
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