CD130/gp130 Protein (Fc Tag)
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- Target See all CD130/gp130 (IL6ST) Proteins
- CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD130/gp130 protein is labelled with Fc Tag.
- Sequence
- CD130(Glu23-Glu619)+hFc(Glu99-Ala330)
- Characteristics
- Tagged Protein: C-Human Fc tag
- Purification
- affinity purification
- Top Product
- Discover our top product IL6ST Protein
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Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 23-122) protein (GST tag)
IL6ST Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (Active) protein (His tag)IL6ST Origin: Mouse Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (Active) protein (His tag,Fc Tag)IL6ST Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (Active) protein (His tag)IL6ST Origin: Rat Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 642-918) protein (His tag)Crystallography grade IL6ST Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 640-917) protein (His tag)Crystallography grade IL6ST Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 23-619) protein (His tag)Crystallography grade IL6ST Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 23-918) protein (rho-1D4 tag)Crystallography grade IL6ST Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 23-917) protein (rho-1D4 tag)Crystallography grade IL6ST Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Preservative
- Without preservative
- Storage
- -80 °C
- Storage Comment
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
- Expiry Date
- 12 months
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- Target
- CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
- Alternative Name
- CD130 (IL6ST Products)
- Synonyms
- CD130 Protein, CDW130 Protein, GP130 Protein, IL-6RB Protein, 5133400A03Rik Protein, AA389424 Protein, BB405851 Protein, D13Ertd699e Protein, gp130 Protein, Ac1055 Protein, Gp130 Protein, Il-6rb Protein, IL-6 Protein, interleukin 6 signal transducer Protein, IL6ST Protein, Il6st Protein, il6st Protein
- Background
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Synonymes: CD130, CDW130, GP130, IL-6RB
Description: The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. - Molecular Weight
- 91.19 kDa
- UniProt
- P40189
- Pathways
- JAK-STAT Signaling, Cellular Glucan Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Cancer Immune Checkpoints
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