CCR4 Protein (Fc Tag)
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- Target See all CCR4 Proteins
- CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CCR4 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human CCR4 with C-terminal human Fc tag
- Specificity
- CCR4 (Met1-Glu39) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- affinity purification
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Preservative
- Without preservative
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
- Alternative Name
- CCR4 (CCR4 Products)
- Synonyms
- CC-CKR-4 Protein, CD194 Protein, CKR4 Protein, CMKBR4 Protein, ChemR13 Protein, HGCN:14099 Protein, K5-5 Protein, Ccr4 Protein, C-C CKR-4 Protein, CHEMR1 Protein, Cmkbr4 Protein, LESTR Protein, Sdf1r Protein, C-C motif chemokine receptor 4 Protein, chemokine (C-C motif) receptor 4 Protein, CCR4 Protein, Ccr4 Protein
- Background
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Synonymes: CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4, HGCN:14099, K5-5
Description: The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. - Molecular Weight
- predicted molecular mass of 30.6 kDa after removal of the signal peptide.The apparent molecular mass of CCR4-hFc is 35-55 kDa due to glycosylation.
- UniProt
- P51679
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