CCR4 Protein-VLP
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- Target See all CCR4 Proteins
- CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
- Protein Type
- VLP
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human CCR4 full length protein-VLP
- Characteristics
- Full Length Transmembrane Proteins
- Top Product
- Discover our top product CCR4 Protein
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Chemokine (C-C Motif) Receptor 4 (CCR4) protein (Fc Tag)
CCR4 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 1-360) protein (Strep Tag)Crystallography grade CCR4 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 1-360) protein (Strep Tag)Crystallography grade CCR4 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Comment
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Virus-like particles (VLPs) are self-assembling multi-protein nanoparticles with similar structural organization and conformation as viruses but without viral genome. The size of the VLP is about 100-150nm. It is secreted from the surface of the cells that express target membrane proteins (MPs). The purified VLPs have the target MPs inserted in a complete bilayer phospholipid membrane structure, mimic the natural membrane-penetrating state of the protein.
VLPs can be used for routine biochemical analysis, including ELISA, SPR affinity analysis, phage display screenings, protein labeling and cell binding experiments, Flow virometry analysis, etc. It can also be used as functional protein antigens to develop active antibodies with high drug potentials because the target protein on VLP exhibits a state like its native state on the cell surface. - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in 1xPBS ( pH 7.4)
- Storage
- -80 °C
- Storage Comment
- The product should be stored at -80°C. Please do not repeated freeze-thaw cycles.
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- Target
- CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
- Alternative Name
- CCR4 (CCR4 Products)
- Synonyms
- CC-CKR-4 Protein, CD194 Protein, CKR4 Protein, CMKBR4 Protein, ChemR13 Protein, HGCN:14099 Protein, K5-5 Protein, Ccr4 Protein, C-C CKR-4 Protein, CHEMR1 Protein, Cmkbr4 Protein, LESTR Protein, Sdf1r Protein, C-C motif chemokine receptor 4 Protein, chemokine (C-C motif) receptor 4 Protein, CCR4 Protein, Ccr4 Protein
- Background
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CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4
Description: The protein belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. - Molecular Weight
- The human full length CCR4 Protein has a MW of 41.4 kDa
- UniProt
- P51679
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