CCR7 Protein (Fc Tag)
CCR7
Origin: Human
Host: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Target See all CCR7 Proteins
- CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CCR7 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human CCR7 with C-terminal human Fc tag
- Specificity
- CCR7 (Glu25-Trp59) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- affinity purification
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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Chemokine (C-C Motif) Receptor 7 (CCR7) protein (Myc-DYKDDDDK Tag)
CCR7 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Preservative
- Without preservative
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
- Alternative Name
- CCR7 (CCR7 Products)
- Synonyms
- zgc:165629 Protein, ccr7-a Protein, CD197 Protein, Cdw197 Protein, Cmkbr7 Protein, EBI1 Protein, Ebi1h Protein, BLR2 Protein, CDw197 Protein, CMKBR7 Protein, chemokine (C-C motif) receptor 7 Protein, C-C motif chemokine receptor 7 Protein, C-C motif chemokine receptor 7 L homeolog Protein, ccr7 Protein, CCR7 Protein, ccr7.L Protein, Ccr7 Protein
- Background
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Synonymes: BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1
Description: The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. - Molecular Weight
- predicted molecular mass of 30.2 kDa after removal of the signal peptide. The apparent molecular mass of CCR7-hFc is 35-55 kDa due to glycosylation.
- UniProt
- P32248
- Pathways
- Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
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