CEACAM1 Protein (His tag)

Catalog No. ABIN6964151

Product Details

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CEACAM1 protein is labelled with His tag.

Purpose: Recombinant human CEACAM1 protein with C-terminal 6xHis tag

Specificity: CEACAM1 (Gln35-Gly428) 6xHis tag

Characteristics: Extracellular Domain Protein

Purification: affinity purification

Purity: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Preservative: Without preservative

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Alternative Name: CEACAM1 (CEACAM1 Products)

Synonyms: BGP Protein, BGP1 Protein, BGPI Protein, CD66e Protein, CEA Protein, zeh0068 Protein, hm:zeh0068 Protein, CEACAM8 Protein, CEACAM1 Protein, MGC142545 Protein, BGPR Protein, Bgp Protein, CD66a Protein, Ccam1 Protein, Bgp1 Protein, C-CAM Protein, Cc1 Protein, Cea-1 Protein, Cea-7 Protein, Cea1 Protein, Cea7 Protein, Hv-2 Protein, Hv2 Protein, MHVR Protein, MHVR1 Protein, Mhv-1 Protein, bb-1 Protein, mCEA1 Protein, mmCGM1 Protein, mmCGM1a Protein, mmCGM2 Protein, carcinoembryonic antigen related cell adhesion molecule 1 Protein, carcinoembryonic antigen related cell adhesion molecule 5 Protein, carcinoembryonic antigen-related cell adhesion molecule 1 Protein, carcinoembryonic antigen-related cell adhesion molecule 6 Protein, CEACAM1 Protein, CEACAM5 Protein, ceacam1 Protein, Ceacam1 Protein, LOC101103343 Protein

Background: Synonymes: CEACAM1,CD66a,BGP,BGP1,BGPI
Description: This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.

Molecular Weight: predicted molecular mass of 44.1 kDa after removal of the signal peptide. The apparent molecular mass of CEACAM1-His is 70-100 kDa due to glycosylation.

UniProt: P13688