CNR2 Protein (Fc Tag)

Catalog No. ABIN6964233

Product Details

Target: CNR2 (Cannabinoid Receptor 2 (CNR2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CNR2 protein is labelled with Fc Tag.

Purpose: Recombinant Human CB2 Protein with C-terminal human Fc tag

Specificity: CB2 (Met1-Lys33) (Asn93-Ala104) (Thr173-Asn188) (Ala270-Lys278) hFc (Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purification: affinity purification

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Preservative: Without preservative

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: CNR2 (Cannabinoid Receptor 2 (CNR2))

Alternative Name: CB2 (CNR2 Products)

Synonyms: CNR2 Protein, CB2 Protein, cb2a Protein, cb2b Protein, CB-2 Protein, CX5 Protein, CB2C Protein, CNR2C Protein, CB2-R Protein, cannabinoid receptor 2 Protein, cannabinoid receptor 2 (macrophage) Protein, CNR2 Protein, cnr2 Protein, Cnr2 Protein

Background: Synonymes: CB-2, CB2, CX5
Description: The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008]

Molecular Weight: predicted molecular mass of 33.9 kDa after removal of the signal peptide.The apparent molecular mass of CB2-hFc is 35-55 kDa due to glycosylation.

UniProt: P34972