CCR1 Protein (Fc Tag)
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- Target See all CCR1 Proteins
- CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CCR1 protein is labelled with Fc Tag.
- Purpose
- Recombinant human CCR1 protein with C-terminal human Fc tag
- Specificity
- CCR1 (Met1-Ala34) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- affinity purification
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CCR1 Protein
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Chemokine (C-C Motif) Receptor 1 (CCR1) (AA 256-355) protein (GST tag)
CCR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-C Motif) Receptor 1 (CCR1) (AA 1-355) protein (Strep Tag)Crystallography grade CCR1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Chemokine (C-C Motif) Receptor 1 (CCR1) (AA 1-355) protein (Strep Tag)Crystallography grade CCR1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Preservative
- Without preservative
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))
- Alternative Name
- CCR1 (CCR1 Products)
- Synonyms
- CD191 Protein, CKR-1 Protein, CKR1 Protein, CMKBR1 Protein, HM145 Protein, MIP1aR Protein, SCYAR1 Protein, Cmkbr1 Protein, Mip-1a-R Protein, C-C motif chemokine receptor 1 Protein, chemokine (C-C motif) receptor 1 Protein, CCR1 Protein, Ccr1 Protein
- Background
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Synonymes: CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1
Description: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008] - Molecular Weight
- predicted molecular mass of 30.0 kDa after removal of the signal peptide. The apparent molecular mass of CCR1-hFc is 35-55 kDa due to glycosylation.
- UniProt
- P32246
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