P2RX7 Protein (Fc Tag)
P2RX7
Origin: Human
Host: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Target See all P2RX7 Proteins
- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This P2RX7 protein is labelled with Fc Tag.
- Purpose
- Recombinant human P2RX7 protein with N-terminal human Fc tag
- Specificity
- HFc (Glu99-Ala330) P2RX7 (Ser47-Val334)
- Characteristics
- Extracellular Domain Protein
- Purification
- affinity purification
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product P2RX7 Protein
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Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) protein (GST tag)
P2RX7 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Preservative
- Without preservative
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
- Alternative Name
- P2RX7 (P2RX7 Products)
- Synonyms
- p2xr7 Protein, P2RX7 Protein, P2X7 Protein, AI467586 Protein, P2X(7) Protein, P2X7R Protein, p2x7 Protein, purinergic receptor P2X 7 Protein, purinergic receptor P2X, ligand-gated ion channel, 7 Protein, P2X purinoceptor 7 Protein, P2RX7 Protein, p2rx7 Protein, LOC100458463 Protein, P2rx7 Protein
- Background
- The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.
- Molecular Weight
- predicted molecular mass of 59.2 kDa after removal of the signal peptide. The apparent molecular mass of hFc-P2RX7 is 55-70 kDa due to glycosylation.
- UniProt
- Q99572
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
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