TEK Protein (Fc Tag)
Quick Overview for TEK Protein (Fc Tag) (ABIN6964382)
Target
See all TEK ProteinsProtein Type
Origin
Source
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Purification tag / Conjugate
- This TEK protein is labelled with Fc Tag.
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Sequence
- TIE2 (Trp23-Leu748)+hFc(GLU99-ALA330)
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Characteristics
- Tagged Protein: C-Human Fc tag
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Purification
- affinity purification
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TEK Tyrosine Kinase, Endothelial (TEK) (AA 23-748) (Active) protein (Fc Tag)
TEK Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
TEK Tyrosine Kinase, Endothelial (TEK) (Active) protein (Fc Tag)TEK Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
TEK Tyrosine Kinase, Endothelial (TEK) (Active) protein (His tag)TEK Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
TEK Tyrosine Kinase, Endothelial (TEK) (AA 770-1122) (Active) protein (GST tag,His tag)TEK Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 91 % as determined by SDS-PAGE Active
TEK Tyrosine Kinase, Endothelial (TEK) protein (His tag)TEK Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with deionized water
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Preservative
- Without preservative
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Storage
- -80 °C
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Storage Comment
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
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Expiry Date
- 12 months
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- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
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Alternative Name
- TIE2
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Background
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Synonymes: CD202B, GLC3E, TIE-2, TIE2, VMCM, VMCM1
Description: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014] -
Molecular Weight
- 105.38 kDa
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UniProt
- Q02763
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Pathways
- RTK Signaling, Growth Factor Binding
Target
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