CD43 Protein (Fc Tag)
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- Target See all CD43 (SPN) Proteins
- CD43 (SPN) (Sialophorin (SPN))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD43 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human CD43 Protein with C-terminal human Fc tag
- Specificity
- CD43 (Ser20-Arg253) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- affinity purification
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product SPN Protein
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Sialophorin (SPN) (AA 20-248) protein (His tag)
SPN Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Sialophorin (SPN) (AA 20-253) protein (His tag)SPN Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Sialophorin (SPN) (AA 27-253) protein (His tag)SPN Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Sialophorin (SPN) (AA 1-400) protein (GST tag)SPN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Sialophorin (SPN) (AA 277-400) protein (His tag)Crystallography grade SPN Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Sialophorin (SPN) (AA 272-395) protein (His tag)Crystallography grade SPN Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Sialophorin (SPN) (AA 20-253) protein (His tag)Crystallography grade SPN Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Sialophorin (SPN) (AA 20-248) protein (His tag)Crystallography grade SPN Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Sialophorin (SPN) (AA 20-400) protein (rho-1D4 tag)Crystallography grade SPN Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Sialophorin (SPN) (AA 20-395) protein (rho-1D4 tag)Crystallography grade SPN Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Preservative
- Without preservative
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CD43 (SPN) (Sialophorin (SPN))
- Alternative Name
- CD43 (SPN Products)
- Synonyms
- CD43 Protein, GALGP Protein, GPL115 Protein, LSN Protein, A630014B01Rik Protein, Cd43 Protein, Galgp Protein, Ly-48 Protein, Ly48 Protein, Lsn Protein, Lsn1 Protein, gpL115 Protein, sialophorin Protein, SPN Protein, Spn Protein
- Background
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Synonymes: CD43, GALGP, GPL115, LSN
Description: This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017] - Molecular Weight
- predicted molecular mass of 49.6 kDa after removal of the signal peptide.The apparent molecular mass of CD43-hFc is 55-130 kDa due to glycosylation.
- UniProt
- P16150
- Pathways
- Regulation of Leukocyte Mediated Immunity
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