CD56 Protein (AA 20-718) (His tag)
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- Target See all CD56 (NCAM1) Proteins
- CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 20-718
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD56 protein is labelled with His tag.
- Purpose
- Human NCAM-1 / CD56 Protein, His Tag (MALS verified)
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product NCAM1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 500 mM NaCl, pH 8.0
- Storage
- -20 °C
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- Target
- CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
- Alternative Name
- NCAM-1 (NCAM1 Products)
- Synonyms
- CD56 Protein, MSK39 Protein, NCAM Protein, fj56g09 Protein, ncam Protein, ncam1 Protein, wu:fj56g09 Protein, NCAM1 Protein, n-cam Protein, E-NCAM Protein, NCAM-1 Protein, Ncam Protein, Cd56 Protein, N-CAM Protein, N-CAM-1 Protein, NCAM-C Protein, NCAMC Protein, N-CAM-1-B Protein, NCAM-1-B Protein, ncam1-a Protein, ncam1-b Protein, neural cell adhesion molecule 1 Protein, neural cell adhesion molecule 1a Protein, neural cell adhesion molecule 1 S homeolog Protein, neural cell adhesion molecule 1 L homeolog Protein, NCAM1 Protein, ncam1a Protein, ncam1 Protein, LOC100085373 Protein, ncam1.S Protein, Ncam1 Protein, ncam1.L Protein
- Background
- NCAM1 belongs to the immunoglobulin superfamily of adhesion molecules. A wide range of alternatively spliced NCAM1 messenger RNAs (mRNAs) has been described to date, but only the 120-, 140-, and 180- kDa isoforms are commonly expressed. NCAM1 plays an important role in the regulation of neurogenesis, neurite outgrowth, proliferation, and cell migration, however, its function in hematopoiesis, including NK cells, is poorly understood. NCAM1 signaling is mediated either by homophilic or heterophilic interactions with fibroblast growth factor receptor (FGFR), L1-CAM, N-cadherin and other components of the extracellular matrix. Upon activation, NCAM1 triggers a variety of signaling cascades including FYN-focal adhesion kinase (FAK), MAPK, and phosphatidylinositol 3-kinase (PI3K) pathways.
- Molecular Weight
- 79.3 kDa
- NCBI Accession
- NP_851996
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