Netrin 1 Protein (NTN1) (AA 22-604) (His tag)
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- Target See all Netrin 1 (NTN1) Proteins
- Netrin 1 (NTN1)
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 22-604
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Netrin 1 protein is labelled with His tag.
- Purpose
- Human Netrin-1 Protein, His Tag
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product NTN1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4 with NaCl
- Storage
- -20 °C
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- Target
- Netrin 1 (NTN1)
- Alternative Name
- Netrin-1 (NTN1 Products)
- Synonyms
- ntn1-A Protein, Netrin-1 Protein, NTN1 Protein, unc-6 Protein, MGC147073 Protein, NTN1L Protein, AI561871 Protein, BC019633 Protein, netrin-1 Protein, netrin 1 L homeolog Protein, netrin 1 Protein, ntn1.L Protein, NTN1 Protein, ntn1 Protein, Ntn1 Protein
- Background
- Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion. Involved in dorsal root ganglion axon projection towards the spinal cord. It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.
- Molecular Weight
- 67.5 kDa
- NCBI Accession
- NP_004813
- Pathways
- Regulation of Cell Size
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