ACE2 Protein (AA 18-740) (mFc Tag)
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- Target See all ACE2 Proteins
- ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 18-740
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ACE2 protein is labelled with mFc Tag.
- Characteristics
- Human ACE2 / ACEH Protein, Mouse IgG1 Fc Tag (MALS verified)
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product ACE2 Protein
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Angiotensin I Converting Enzyme 2 (ACE2) protein (His tag,AVI tag,Biotin)
ACE2 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. SDS, Func
Angiotensin I Converting Enzyme 2 (ACE2) protein (His tag)ACE2 Origin: Paguma larvata Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. SDS
Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-740) protein (Fc Tag)ACE2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Angiotensin I Converting Enzyme 2 (ACE2) protein (His-Avi Tag,Biotin)ACE2 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Angiotensin I Converting Enzyme 2 (ACE2) protein (His-Avi Tag)ACE2 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Angiotensin I Converting Enzyme 2 (ACE2) protein (His-Avi Tag)ACE2 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-740) protein (His tag)ACE2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-740) protein (Fc-Avi Tag,Biotin)ACE2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Angiotensin I Converting Enzyme 2 (ACE2) protein (mFc Tag)ACE2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Angiotensin I Converting Enzyme 2 (ACE2) protein (His-Avi Tag,Biotin)ACE2 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
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- Application Notes
- MALS verified
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 50 mM Tris, 150 mM NaCl, Arginine, pH 7.5
- Storage
- -80 °C
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- Target
- ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
- Alternative Name
- ACE2 (ACE2 Products)
- Synonyms
- ACE1 Protein, CD143 Protein, DCP Protein, DCP1 Protein, ICH Protein, MVCD3 Protein, ACEH Protein, 2010305L05Rik Protein, zgc:92514 Protein, angiotensin I converting enzyme Protein, angiotensin I converting enzyme 2 Protein, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 Protein, ACE Protein, ACE2 Protein, Ace2 Protein, ace2 Protein
- Background
- Angiotensin-converting enzyme 2 (ACE2) is also known as ACEH (ACE homolog), is an integral membrane protein with considerable homologous to ACE, which belongs to the peptidase M2 family. ACE2 is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin, or the conversion of angiotensin II to angiotensin 1-7. ACE2 may be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, ACE-2 serve as functional receptor for the spike glycoprotein of both coronaviruses. ACE2 is activated by chloride and fluoride, but not bromide and Inhibited by MLN-4760, cFP_Leu, and EDTA, but not by the ACE inhibitors linosipril, captopril and enalaprilat. ACE2 is active from pH 6 to 9, and the optimum pH is 6.5 in the presence of 1 M NaCl.
- Molecular Weight
- 109.8 kDa
- NCBI Accession
- NP_068576
- Pathways
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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