CD8 Protein (CD8) (AA 22-182) (His tag)
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- Target See all CD8 Proteins
- CD8
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 22-182
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD8 protein is labelled with His tag.
- Characteristics
- Human CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His Tag&Tag Free (MALS verified)
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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CD8 (CD8) (AA 22-182) (Active) protein (His tag,FITC)
CD8 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
CD8 (CD8) protein (His tag)CD8 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- MALS verified
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- CD8
- Alternative Name
- CD8 alpha & beta (CD8 Products)
- Synonyms
- CD8 Protein, Leu2 Protein, MAL Protein, p32 Protein, CD8a molecule Protein, CD8A Protein
- Background
- Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfide-linked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells. Additionally, CD8B plays a critical role in thymic selection of CD8+ T-cells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.
- Molecular Weight
- 19.5 kDa (CD8A) & 22.1 kDa (CD8B)
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