ILDR2 Protein (AA 21-186) (Fc Tag)
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- Target See all ILDR2 products
- ILDR2 (Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-186
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ILDR2 protein is labelled with Fc Tag.
- Characteristics
- Human ILDR2 Protein, Fc Tag
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 21-184) protein (Fc Tag)
ILDR2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 92 % as determined by HPLC
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) protein (His tag)ILDR2 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 21-186) protein (His tag)Crystallography grade ILDR2 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, Crys, ELISA, WB
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 36-201) protein (His tag)Crystallography grade ILDR2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, Crys, ELISA, WB
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 208-639) protein (His tag)Crystallography grade ILDR2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, Crys, ELISA, WB
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 223-661) protein (His tag)Crystallography grade ILDR2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, Crys, ELISA, WB
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 21-639) protein (rho-1D4 tag)Crystallography grade ILDR2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, Crys, ELISA, WB
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 36-661) protein (rho-1D4 tag)Crystallography grade ILDR2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, Crys, ELISA, WB
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 1-186), (Extracellular) protein (GST tag)ILDR2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 1-186), (Extracellular) protein (His tag)ILDR2 Origin: Human Host: Yeast Recombinant > 90 % SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- ILDR2 (Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2))
- Alternative Name
- ILDR2 (ILDR2 Products)
- Synonyms
- C1orf32 Protein, RP4-782G3.2 Protein, dJ782G3.1 Protein, immunoglobulin like domain containing receptor 2 Protein, ILDR2 Protein
- Background
- ILDR2 belongs to the immunoglobulin superfamily. May be involved in lipid homeostasis and ER stress pathways. ILDR2 as a novel B7-like protein with robust T cell inhibitory activity, expressed in immune cells and in immune-privileged and inflamed tissues. A fusion protein, consisting of ILDR2 extracellular domain with an Fc fragment, that binds to a putative counterpart on activated T cells showed a beneficial effect in the collagen-induced arthritis model and abrogated the production of proinflammatory cytokines and chemokines in autologous synovial-like cocultures of macrophages and cytokine-stimulated T cells. Collectively, these findings point to ILDR2 as a novel negative regulator for T cells, with potential roles in the development of immune-related diseases, including autoimmunity and cancer.
- Molecular Weight
- 45.1 kDa
- NCBI Accession
- NP_955383
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